scMatchmaker is an R package that uncovers cell-cell interactions in single cell RNA-seq data. It uses Earth Mover's Distance of ligand-receptor expressions and a permutation test to identify significant interactions in the data. It allows users to input customized interaction information or load the CellPhoneDB ligand-receptor database, and provides essential visualization tools.
Useful links:
Report bugs at https://github.com/stevexniu/scMatchmaker/issues