Merge Interactions

Merge directed (one-way) interactions into undirected (two-way) interactions. For example, before merging, DC1|dM1 and dM1|DC1 represents two different cell-cell interactions. After merging, they will be combined as one undirected cell-cell interaction between DC1 and dM1.

Merging(
  object,
  strength_merge = c("max", "average", "min"),
  pval_merge = c("min", "average", "max")
)

Arguments

object

Matchmaker object.

strength_merge

Method to combine complex interaction strength from its subunits. Default is max (maximum).

• max, maximum strength of directed interactions.

• average, average strength of directed interactions.

• min, minimum strength of directed interaction.

pval_merge

Method to combine complex interaction p value from its subunits. Default is min (minimum).

• min, minimum p value of directed interactions.

• average, average p value of directed interactions.

• max, maximum p value of directed interactions.

Value

Returns a Matchmaker object.

Examples

if (FALSE) {
object <- Merging(object, strength_merge = "average", pval_merge = "max")
}